Systems Biology Publications

Publications in Systems Biology

Explore the most influential research papers and scholarly works that have shaped Systems Biology. Use the concept filter below to focus on a specific sub-area of research.

Systems Biology

232.1K

Publications

21.2M

Citations

Showing yearly statistics from 2000-2026.

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	Year	Citations
Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method Kenneth J. Livak, Thomas D. Schmittgen Methods Functional GenomicsEngineeringMedicineGeneticsGene Recognition	2001	176.9K
Basic local alignment search tool Stephen F. Altschul, Warren Gish, Webb Miller, Journal of Molecular Biology BioinformaticsEngineeringInformation RetrievalString-searching AlgorithmString Processing	1990	92.8K
Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles Aravind Subramanian, Pablo Tamayo, Vamsi K. Mootha, Proceedings of the National Academy of Sciences GeneticsGenomicsGene RecognitionBioinformatics DatabaseGene Expression Profiling	2005	54.5K
UCSF Chimera—A visualization system for exploratory research and analysis Eric F. Pettersen, Thomas D. Goddard, Conrad C. Huang, Journal of Computational Chemistry Interactive VisualizationExtensible Visualization SystemUcsf ChimeraEngineeringData Science	2004	46.8K
MAFFT Multiple Sequence Alignment Software Version 7: Improvements in Performance and Usability Kazutaka Katoh, Daron M. Standley Molecular Biology and Evolution GeneticsMolecular BiologyMajor UpdateGenomicsSequence Alignment	2013	45.6K
MUSCLE: multiple sequence alignment with high accuracy and high throughput R. C. Edgar Nucleic Acids Research GeneticsMolecular BiologyGenomicsSequence AlignmentMuscle Program	2004	45.3K
Gene Ontology: tool for the unification of biology Michael Ashburner, Catherine A. Ball, Judith A. Blake, Nature Genetics Functional GenomicsEngineeringBioinformatics DatabaseBiological DatabaseMedicine	2000	43.3K
limma powers differential expression analyses for RNA-sequencing and microarray studies Matthew E. Ritchie, Belinda Phipson, Di Wu, Nucleic Acids Research GeneticsMolecular BiologyTranscriptomics TechnologyLimma PackageGenomics	2015	40.9K
The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools Julie Thompson Nucleic Acids Research EngineeringGeneticsMolecular BiologyGenomicsSequence Alignment	1997	39.1K
BIOEDIT: A USER-FRIENDLY BIOLOGICAL SEQUENCE ALIGNMENT EDITOR AND ANALYSIS PROGRAM FOR WINDOWS 95/98/ NT T. A. Hall Nucleic Acids Symposium Series BioinformaticsEngineeringBioinformatics DatabaseMolecular EcologyGene Sequence Annotation	1999	38.7K
Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources Da Wei Huang, Brad T. Sherman, Richard A. Lempicki Nature Protocols BiologyFunctional GenomicsLarge Gene ListsEngineeringBiological Database	2008	36.7K
clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters Guangchuang Yu, Li-Gen Wang, Yanyan Han, OMICS A Journal of Integrative Biology GeneticsGenomicsGene RecognitionBioinformatics DatabaseR Package	2012	36K

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